A second forelimb motor area exists in rat frontal cortex

• Published in: Brain research Vol. 232; no. 1; p. 151
• Main Authors: Neafsey, E J, Sievert, C
• Format: Journal Article
• Language: English
• Published: Netherlands 01-01-1982
• Subjects: Animals; Cerebral Cortex - physiology; Electric Stimulation; Evoked Potentials; Forelimb - innervation; Motor Activity; Rats
• ISSN: 0006-8993
• DOI: 10.1016/0006-8993(82)90617-5

Intracortical microstimulation of 40--50 points in the frontal cortex of ketamine-anesthetized rats using perpendicular penetrations has demonstrated a second forelimb area located rostrally near the frontal pole as well as confirming the existence of a more caudally located forelimb area just anterior to bregma. Cortex where neck and/or vibrissae movements were evoked separated the two forelimb areas. The rostral and caudal forelimb areas defined by microstimulation correspond with patches of corticospinal neurons labeled with HRP following injections of this tracer into the cervical enlargement. Digit movements were commonly evoked from the rostral forelimb area but were rarely elicited from the caudal forelimb area. The question of whether the rostral forelimb region is part of primary or supplementary motor cortex is not yet able to be answered.