Comparative analysis of three sensitins used in cutaneous testing for tuberculosis and paratuberculosis in cattle

Correspondence between components of sensitins (avian, bovine, and johnin-PPD tuberculins) and the proteins of the corresponding microorganisms (Mycobacterium avium, Mycobacterium bovis and Mycobacterium paratuberculosis) was established. Most of these identified proteins are present in the three or...

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Bibliographic Details
Published in:	FEMS microbiology letters Vol. 110; no. 3; p. 307
Main Authors:	Gilot, P, Cocito, C
Format:	Journal Article
Language:	English
Published:	England 01-07-1993
Subjects:	Animals Bacterial Proteins - analysis Cattle Hypersensitivity, Delayed Mycobacterium - chemistry Mycobacterium avium - chemistry Mycobacterium avium subsp. paratuberculosis - chemistry Mycobacterium bovis - chemistry Paratuberculosis - diagnosis Skin Tests Species Specificity Tuberculin - chemistry Tuberculosis, Bovine - diagnosis
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Summary:	Correspondence between components of sensitins (avian, bovine, and johnin-PPD tuberculins) and the proteins of the corresponding microorganisms (Mycobacterium avium, Mycobacterium bovis and Mycobacterium paratuberculosis) was established. Most of these identified proteins are present in the three organisms, but the 38.3- and 48.8-kDa proteins of M. avium and the 54.0- and 58.7-kDa proteins of M. bovis are endowed with species-specific epitope(s).
ISSN:	0378-1097
DOI:	10.1111/j.1574-6968.1993.tb06340.x