Midbrain central gray: LHRH infusion enhances lordotic behavior in estrogen-primed ovariectomized rats

Ovariectomized rats were implanted with 23 gauge stainless steel cannulae in the ventrolateral midbrain central gray. Twelve sexually active rats were estrone-primed and infused with saline and 50 ng luteinizing hormone-releasing hormone (LHRH) in counterbalanced order. Infusion of luteinizing hormo...

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Bibliographic Details
Published in:	Brain research bulletin Vol. 4; no. 2; p. 203
Main Authors:	Riskind, P, Moss, R L
Format:	Journal Article
Language:	English
Published:	United States 01-03-1979
Subjects:	Animals Castration Estrone - pharmacology Female Gonadotropin-Releasing Hormone - pharmacology Hypothalamus - drug effects Mesencephalon - drug effects Progesterone - pharmacology Rats Sexual Behavior, Animal - drug effects
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Summary:	Ovariectomized rats were implanted with 23 gauge stainless steel cannulae in the ventrolateral midbrain central gray. Twelve sexually active rats were estrone-primed and infused with saline and 50 ng luteinizing hormone-releasing hormone (LHRH) in counterbalanced order. Infusion of luteinizing hormone-releasing hormone significantly enhanced the lordotic response to coital stimulation compared to saline infusion. These results support the role of hypothalamo-mesencephalic LHRH-containing pathways in modulating lordotic behavior in estrogen-primed ovariectomized rats.
ISSN:	0361-9230
DOI:	10.1016/0361-9230(79)90282-X