How Does Medical Policy on the Use of Prophylactic Antibiotics Affect Medical Costs, Length of Hospital Stay, and Antibiotic Use in Orthopedics?

• Published in: Yonsei medical journal Vol. 64; no. 3; pp. 213 - 220
• Main Authors: Kim, Seung Hoon, Jang, Suk-Yong, Cha, Yonghan, Kim, Bo-Yeon, Lee, Hyo-Jung, Kim, Gui-Ok
• Format: Journal Article
• Language: English
• Published: Korea (South) Yonsei University College of Medicine 01-03-2023; 연세대학교의과대학
• Subjects: Anti-Bacterial Agents - therapeutic use; Humans; Length of Stay; Original; Policy; Retrospective Studies; 의학일반; Antibiotic prophylaxis; medical policy; orthopedic surgery
• ISSN: 0513-5796; 1976-2437
• DOI: 10.3349/ymj.2022.0546

The purpose of this study was to compare patients who had undergone spine surgery (SS) and hip arthroplasty surgery (HAS) and to analyze how medical policies drawn from "The Evaluation of the Appropriate Use of Prophylactic Antibiotics" have affected length of hospital stay (LOS), direct medical costs (DMC), and the duration of antibiotics use in Korea.
This retrospective nationwide study identified subjects from the Korean National Health Insurance Review and Assessment Service database from January, 2011 to December, 2018. Evaluation of HAS (control group) was implemented in 2007, and that for SS (case group) was conducted for the first time in 2014 (intervention time). In our comparative interrupted time series analysis, we compared DMC, LOS, and use of antibiotics between both groups.
177468 patients who underwent SS and 89372 patients who underwent HAS were included in the study. In 2016, DMC increased for HAS, compared to SS, by 1.03 times (
=0.041). However, cost changes during other observational periods for SS were not higher than those for HAS (
>0.05). SS incurred a reduced LOS of 3% in the first 2 years (
<0.05). Thereafter, LOS changes in SS were not smaller than those in HAS. A decrease in the usage of total antibiotics and broad spectrum antibiotics was observed for 5 years.
This medical policy was effective in terms of reducing usage and duration of antibiotics use, especially in the first 2 years after the implementation of the policy.