A Novel Approach to Synthesize TiO2 Nanoparticles: Biosynthesis by Using Streptomyces sp. HC1

• Published in: Journal of inorganic and organometallic polymers and materials Vol. 30; no. 8; pp. 3221 - 3229
• Main Authors: Ağçeli, Gözde Koşarsoy, Hammachi, Hamideh, Kodal, S. Pınar, Cihangir, Nilüfer, Aksu, Zümriye
• Format: Journal Article
• Language: English
• Published: New York Springer US 01-08-2020; Springer Nature B.V
• Subjects: Antiinfectives and antibacterials; Antimicrobial agents; Atomic beam spectroscopy; Atomic force microscopy; Bacteria; Biosynthesis; Chemistry; Chemistry and Materials Science; E coli; Fungi; Inorganic Chemistry; Microscopy; Nanoparticles; Organic Chemistry; Polymer Sciences; Pseudomonas aeruginosa; Surgical implants; Titanium dioxide; Nanoparticles; Antimicrobial; Characterization; TiO; Biological synthesis
• ISSN: 1574-1443; 1574-1451
• DOI: 10.1007/s10904-020-01486-w

A simple, yet effective and rapid approach for the synthesis of titanium dioxide nanoparticles (TiO
2
NPs) using
Streptomyces
sp. HC1 was developed. The in vitro activity of TiO
2
NPs was demonstrated against human pathogenic bacteria and fungi. The synthesized nanoparticles were characterized using various methods and instruments, such as Zetasizer, X-ray diffraction, Fourier transmission infrared spectroscopy, atomic force microscopy, and scanning electron microscopy. TiO
2
NPs were observed to be spherical in shape with size in the range of 30 to 70 nm. Antimicrobial activities of TiO
2
NPs against
Staphylococcus aureus
ATCC 29213,
Escherichia coli
ATCC 35218,
Candida albicans
, ATCC 10231, and
Aspergillus niger
ATCC 6275 were evaluated. It was observed that TiO
2
NPs showed higher antimicrobial activity against bacteria (12 mm) than against fungi. Moreover, TiO
2
NPs also showed potent antibiofilm activity against
Pseudomonas aeruginosa
ATCC 27853. Hence, the present study highlights the biological synthesis and characterization of TiO
2
NPs, and their applications in the field of biomedical sciences.