Antimicrobial resistance of strains of the Bacteroides fragilis group isolated from the intestinal tract of children and adults in Brazil

• Published in: International journal of antimicrobial agents Vol. 18; no. 2; pp. 129 - 134
• Main Authors: Avelar, Kátia Eliane S., Vieira, Jéssica Manya B.D., Antunes, Luis Caetano M., Lobo, Leandro A., Antunes, Eduardo Nazareno F., Domingues, Regina Maria C.P., Ferreira, Maria Candida S.
• Format: Journal Article
• Language: English
• Published: London Elsevier B.V 01-08-2001; Amsterdam Elsevier; New York, NY
• Subjects: Adult; Anti-Bacterial Agents - pharmacology; Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antimicrobial resistance; Bacteroides - drug effects; Bacteroides - enzymology; Bacteroides - isolation & purification; Bacteroides distasonis; Bacteroides fragilis; Bacteroides fragilis - drug effects; Bacteroides fragilis - enzymology; Bacteroides fragilis group; beta-Lactamases - metabolism; Biological and medical sciences; Brazil; Child; Child, Preschool; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Infant; Intestines - microbiology; Medical sciences; Microbial Sensitivity Tests; Microflora; Pharmacology. Drug treatments; South America; Brazil; America; Microflora; Antimicrobial resistance; Bacteroides fragilis group; Human; Drug susceptibility test; Enzyme; Digestive system; Bacteroides fragilis; Gut; β-Lactamase; In vitro; Bacteroidaceae; Resistance; Antibiotic; Minimum inhibitory concentration; Bacteria; Hydrolases; Adult; Antibacterial agent; Child
• ISSN: 0924-8579; 1872-7913
• DOI: 10.1016/S0924-8579(01)00354-5

The results of this study show that there is a high frequency of resistant species in the
Bacteroides fragilis group in the intestinal tract of children and adults in Brazil.
B. fragilis was not studied. Of the 73 strains examined,
B. distasonis was the most resistant species to penicillin, cefoxitin, cefotaxime and clindamycin. High rates of multiresistance were found, most commonly to penicillin and clindamycin (18 of 36 strains). High levels of β-lactamase production were detected in isolates showing high resistance to penicillin and multiresistance to the cephamycins, suggesting a widespread dissemination of such resistance.