Acute and chronic toxicity testing of bisphenol A with aquatic invertebrates and plants

• Published in: Ecotoxicology and environmental safety Vol. 72; no. 5; pp. 1392 - 1399
• Main Authors: Mihaich, Ellen M., Friederich, Urs, Caspers, Norbert, Hall, A. Tilghman, Klecka, Gary M., Dimond, Stephen S., Staples, Charles A., Ortego, Lisa S., Hentges, Steven G.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01-07-2009
• Subjects: Amphipoda - drug effects; Animals; Aquatic plants; Araceae - drug effects; Araceae - growth & development; Benzhydryl Compounds; Bisphenol A; BPA; Brachionus calyciflorus; Chironomid; Chironomidae - drug effects; Chironomus tentans; Diphenols; Dose-Response Relationship, Drug; Environmental Monitoring - methods; Epoxy resins; Female; Fish; Freshwater; Hyalella; Hyalella azteca; Invertebrata; Invertebrate; Invertebrates; Invertebrates - drug effects; Invertebrates - growth & development; Lemna; Lemna gibba; Lethal Dose 50; Male; Marisa cornuarietis; Mollusca; Mollusks; No-Observed-Adverse-Effect Level; Phenols - toxicity; Polycarbonates; Population Density; Rotifer; Rotifera; Rotifera - drug effects; Snail; Snails - drug effects; Toxicity testing; Toxicity Tests, Acute - methods; Toxicity Tests, Chronic - methods; Water Pollutants, Chemical - toxicity; Invertebrate; BPA; Chironomid; Hyalella; Lemna; Snail; Rotifer
• ISSN: 0147-6513; 1090-2414
• DOI: 10.1016/j.ecoenv.2009.02.005

Bisphenol A (BPA, 4,4′-isopropylidine diphenol) is a commercially important chemical used primarily as an intermediate in the production of polycarbonate plastic and epoxy resins. Extensive effect data are currently available, including long-term studies with BPA on fish, amphibians, crustaceans, and mollusks. The aim of this study was to perform additional tests with a number of aquatic invertebrates and an aquatic plant. These studies include acute tests with the midge (
Chironomus tentans) and the snail (
Marisa cornuarietis), and chronic studies with rotifers (
Brachionus calyciflorus), amphipods (
Hyalella azteca), and plants (
Lemna gibba). The effect data on different aquatic invertebrate and plant species presented in this paper correspond well with the effect and no-effect concentrations (NOECs) available from invertebrate studies in the published literature and are within the range found for other aquatic species tested with BPA.