Postexercise Hemodynamic Responses in Lean and Obese Men

• Published in: Medicine and science in sports and exercise Vol. 50; no. 11; pp. 2292 - 2300
• Main Authors: ZEIGLER, ZACHARY S, SWAN, PAMELA D, BUMAN, MATTHEW P, MOOKADAM, FAROUK, GAESSER, GLENN A, ANGADI, SIDDHARTHA S
• Format: Journal Article
• Language: English
• Published: United States American College of Sports Medicine 01-11-2018
• Subjects: Adaptation, Physiological; Adolescent; Adult; Blood Pressure; Brachial Artery - physiology; Cardiac Output; Carotid Arteries - physiology; Exercise - physiology; Exercise Therapy; Femoral Artery - physiology; Hemodynamics; Humans; Hypotension - etiology; Hypotension - physiopathology; Male; Obesity, Abdominal - physiopathology; Obesity, Abdominal - therapy; Physical Conditioning, Human - adverse effects; Pulse Wave Analysis; Stroke Volume; Thinness - physiopathology; Vascular Resistance; Young Adult
• ISSN: 0195-9131; 1530-0315
• DOI: 10.1249/MSS.0000000000001684

PURPOSEWe assessed resting central/peripheral blood pressure (BP), postexercise BP, and hemodynamic responses (stroke volume, cardiac output, and systemic vascular resistance) after acute exercise and 2 wk of aerobic training in lean and centrally obese men matched for BP.
METHODSEight lean (body mass index < 25 kg·m, visceral fat = 279 ± 224 cm) and eight centrally obese (body mass index > 30 kg·m, visceral fat = 1471 ± 374 cm) men performed six training sessions (3 d·wk for 40 min at 65%–70% HRmax). Resting BP and hemodynamic measurements were obtained at baseline, after exercise for 60 min, and at 24 h and 48 h after the last training session.
RESULTSPostexercise brachial and central systolic BP (SBP) and mean arterial BP decreased 3–4 mm Hg below resting in lean (P < 0.001) and increased by 3 mm Hg in obese (P < 0.02). Posttraining resting brachial/central SBP were reduced by 3–4 mm Hg only in lean men (P < 0.05). Pretraining postexercise hypotension was significantly correlated with the training-induced change in resting brachial SBP at 48 h (r = 0.58, P = 0.02), but not at 24 h (r = 0.38, P = 0.15). Similar correlations were observed between acute reductions in central SBP and central SBP at 24 h (r = 0.43, P = 0.09) and 48 h (r = 0.54, P = 0.03) posttraining.
CONCLUSIONSIn contrast to the consistent results for lean men, postexercise hypotension was not observed in centrally obese men, and resting SBP was not reduced after a short aerobic training program. Considerable individual variation in postexercise BP response among obese men may have implications for design of exercise interventions to lower BP in these individuals.