Gallbladder selection for histopathological analysis based on a simple method: a prospective comparative study

• Published in: Annals of the Royal College of Surgeons of England Vol. 94; no. 3; pp. 159 - 164
• Main Authors: Romero-González, R J, Garza-Flores, A, Martínez-PérezMaldonado, L, Díaz-Elizondo, J A, Muñiz-Eguía, J J, Barbosa-Quintana, A
• Format: Journal Article
• Language: English
• Published: England The Royal College of Surgeons of England 01-04-2012
• Subjects: Adenocarcinoma - pathology; Adult; Aged; Cholecystectomy - methods; Dissection - methods; Female; Gallbladder Neoplasms - pathology; General Surgery; Humans; Male; Middle Aged; Palpation - methods; Pathology, Clinical - methods; Postoperative Care - methods; Prospective Studies; Referral and Consultation; Unnecessary Procedures - statistics & numerical data
• ISSN: 0035-8843; 1478-7083
• DOI: 10.1308/003588412X13171221589810

After a cholecystectomy, the current and traditional practice is to send each resected gallbladder to the pathologist for analysis. Some reports have suggested the possibility of selecting only those gallbladders that need to be analysed. The purpose of this study was to show a simple method for selecting which gallbladders should be sent to the pathologist.
A prospective comparative study was carried out. Two 'tests' were performed in 150 patients to detect or rule out gallbladder cancer. The first test included the patient's variables and a macroscopic gallbladder analysis performed by the surgeon (MGAS). The second test was the analysis performed by the pathologist. The results were compared.
Of the 150 patients, 132 were women and 18 men; 130 were under 60 years old. One patient had inflammatory bowel disease, seven had changes on ultrasonography and in four cases intra-operative disturbances were observed. During the MGAS, disturbances were found in 30 patients. Eighty-one cases (54%) had at least one or more risk factors for gallbladder cancer.