Hemophagocytic Lymphohistiocytosis Associated with Visceral Leishmaniasis

• Published in: Journal of tropical pediatrics (1980) Vol. 53; no. 5; pp. 359 - 361
• Main Authors: Tapisiz, Anil, Belet, Nurşen, Çıftçı, Ergın, İnce, Erdal, Doğru, Ülker
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01-10-2007; Oxford Publishing Limited (England)
• Subjects: Amphotericin B - therapeutic use; Antiprotozoal Agents - therapeutic use; Biological and medical sciences; Child, Preschool; General aspects; Human protozoal diseases; Humans; Infectious diseases; Leishmaniasis, Visceral - complications; Leishmaniasis, Visceral - diagnosis; Leishmaniasis, Visceral - drug therapy; Leshmaniasis; Lymphohistiocytosis, Hemophagocytic - etiology; Male; Medical sciences; Pancytopenia - etiology; Parasitic diseases; Protozoal diseases; hemophagocytosis; children; Infection; Immunopathology; Hemophagocytic lymphohistiocytosis; Pediatrics; Protozoal disease; Association; Kala azar; Tropical medicine; Leishmaniasis; Parasitosis
• ISSN: 0142-6338; 1465-3664
• DOI: 10.1093/tropej/fmm024

Visceral leishmaniasis (VL), is a systemic disease caused by the dissemination of protozoan parasite Leishmania throughout the reticuloendothelial system. It may mimic or lead to several types of hematological disorders including hemophagocytosis. Infection associated hemophagocytic syndrome implicating Leishmania is very rare and often difficult to diagnose. Here, we describe a child with hemophagocytic lymphohistiocytosis (HLH) associated with VL.