Effect of the Ratio of Resected Tissue in Comparison With the Prostate Transitional Zone Volume on Voiding Function Improvement After Transurethral Resection of Prostate

• Published in: Urology (Ridgewood, N.J.) Vol. 79; no. 1; pp. 202 - 206
• Main Authors: Park, Hyoung Keun, Paick, Sung Hyun, Lho, Yong Soo, Jun, Kyung Kyu, Kim, Hyeong Gon
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 2012; Elsevier
• Subjects: Aged; Aged, 80 and over; Biological and medical sciences; Cohort Studies; Follow-Up Studies; Humans; Lower Urinary Tract Symptoms - etiology; Lower Urinary Tract Symptoms - physiopathology; Male; Medical sciences; Middle Aged; Nephrology. Urinary tract diseases; Organ Size; Postoperative Care - methods; Prostate - anatomy & histology; Prostate - surgery; Prostatic Hyperplasia - complications; Prostatic Hyperplasia - diagnosis; Prostatic Hyperplasia - surgery; Recovery of Function; Retrospective Studies; Severity of Illness Index; Transurethral Resection of Prostate - methods; Treatment Outcome; Urination - physiology; Urination Disorders - etiology; Urination Disorders - physiopathology; Urology; Nephrology; Zone; Surgical resection; Transurethral route; Urology; Tissue; Treatment; Micturition; Volume; Surgery; Surgical approach; Ratio; Urogenital system; Prostate; Comparative study
• ISSN: 0090-4295; 1527-9995
• DOI: 10.1016/j.urology.2011.07.1397

Objective Few studies exist correlating the extent of tissue resected with symptom improvement after transurethral resection of prostate (TURP). This study evaluated the effect of the ratio of resected tissue in comparison with the transitional zone volume (TZV) on improvement of voiding symptoms and flow rate. Methods A total of 263 patients who underwent TURP from January 2001 to June 2008 were included in this retrospective study. TURP efficacy was assessed at 6 months using International Prostate Symptom Score (IPSS) and uroflowmetry. Patients were then stratified into 2 subgroups according to resection ratio (volume of resected tissue/TZV); individuals with resection ratio <50% (group A) and ≥50% (group B). The 2 groups were compared with regard to prostate volume, TZV, preoperative and postoperative IPSS, quality of life (QoL), peak flow rate (Qmax ), and postvoid residual (PVR). Similar analyses were performed according to prostate volume (small [<40 g] vs large [≥40 g]). Results Of these individuals, 85 (32.3%) met the criteria for group A, and 178 (67.7%) for group B. There were no statistically significant differences in age, prostate volume, TZV, preoperative IPSS, QoL score, Qmax , and PVR. After TURP, there was no significant difference of IPSS, QoL score, Qmax , and PVR between the 2 groups. After stratification according to prostate size, the differences in clinical variables were not significant according to resection ratio. Conclusion Resection ratio had no effect on post-TURP clinical improvement. These results suggest that complete prostate adenoma resection may not be essential.