Mycoplasma bovis mastitis in dairy cattle

• Published in: Frontiers in veterinary science Vol. 11; p. 1322267
• Main Authors: Gelgie, Aga E, Desai, Sarah E, Gelalcha, Benti D, Kerro Dego, Oudessa
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 06-03-2024
• Subjects: dairy cows; Mycoplasma bovis; Mycoplasma bovis mastitis; pathogenesis; subclinical mastitis; Veterinary Science; virulence factors; Mycoplasma bovis mastitis; pathogenesis; clinical mastitis; intramammary infection; subclinical mastitis; dairy cows; Mycoplasma bovis; virulence factors
• ISSN: 2297-1769; 2297-1769
• DOI: 10.3389/fvets.2024.1322267

has recently been identified increasingly in dairy cows causing huge economic losses to the dairy industry.
is a causative agent for mastitis, pneumonia, endometritis, endocarditis, arthritis, otitis media, and many other clinical symptoms in cattle. However, some infected cows are asymptomatic or may not shed the pathogen for weeks to years. This characteristic of
, along with the lack of adequate testing and identification methods in many parts of the world until recently, has allowed the
to be largely undetected despite its increased prevalence in dairy farms. Due to growing levels of antimicrobial resistance among wild-type
isolates and lack of cell walls in mycoplasmas that enable them to be intrinsically resistant to beta-lactam antibiotics that are widely used in dairy farms, there is no effective treatment for
mastitis. Similarly, there is no commercially available effective vaccine for
mastitis. The major constraint to developing effective intervention tools is limited knowledge of the virulence factors and mechanisms of the pathogenesis of
mastitis. There is lack of quick and reliable diagnostic methods with high specificity and sensitivity for
. This review is a summary of the current state of knowledge of the virulence factors, pathogenesis, clinical manifestations, diagnosis, and control of
mastitis in dairy cows.