Diastolic suction in heart failure: Impact of left ventricular geometry, untwist, and flow mechanics

• Published in: Life sciences (1973) Vol. 102; no. 2; pp. 111 - 117
• Main Authors: Nogami, Yoshie, Ishizu, Tomoko, Atsumi, Akiko, Yamamoto, Masayoshi, Nakamura, Akihiro, Machino-Ohtsuka, Tomoko, Kawamura, Ryo, Seo, Yoshihiro, Aonuma, Kazutaka
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 02-05-2014
• Subjects: Adult; Aged; Aged, 80 and over; Blood Flow Velocity - physiology; Blood Pressure - physiology; Diastole; Failing heart; Female; Geometry; Heart Failure - diagnosis; Heart Failure - pathology; Heart Failure - physiopathology; Heart Ventricles - anatomy & histology; Heart Ventricles - pathology; Heart Ventricles - physiopathology; Hemodynamics - physiology; Humans; Male; Middle Aged; Suction kinetic energy index; Untwisting; Vectorcardiography - methods; Ventricular Function, Left - physiology; Geometry; Untwisting; Suction kinetic energy index; Failing heart
• ISSN: 0024-3205; 1879-0631
• DOI: 10.1016/j.lfs.2014.03.016

Vector flow mapping (VFM) can be used to assess intraventricular hemodynamics quantitatively. This study assessed the magnitude of the suction flow kinetic energy with VFM and investigated the relation between left ventricular (LV) function and geometry in patients with an estimated elevated LV filling pressure.
We studied 24 subjects with an elevated LV filling pressure (EFP group) and 36 normal subjects (normal group). Suction was defined as flow directed toward the apex during the period from soon after systolic ejection to before mitral inflow. The flow kinetic energy index was quantified as the sum of the product of the blood mass and velocity vector and its magnitude to the peak value was measured.
Suction flow was observed in 12 (50%) EFP-group patients and 36 (100%) normal-group subjects. The magnitude of the suction kinetic energy index was significantly smaller in EFP versus normal group (2.7±3.8 vs. 5.7±4.4g/s/cm2, P<0.01). The EFP-group patients with suction had a smaller LV end-systolic volume (ESV) (P<0.01), greater ellipsoidal geometry (P<0.05) and untwisting rate (P<0.01) than the EFP-group patients without suction. A regression analysis indicated a significant linear relation between the suction kinetic energy index and LVEF (r=0.43, P=0.04), ESV (r=−0.40, P=0.05), eccentricity index (r=0.44, P=0.04), and untwisting rate (r=0.51, P=0.04).
The magnitude of the suction flow kinetic energy index derived from VFM may allow the quantitative assessment of the suction flow, which correlates with LV systolic function, geometry, and untwisting mechanics.