Carbon-based nanomaterials for targeted cancer nanotherapy: recent trends and future prospects

• Published in: Journal of drug targeting Vol. 29; no. 7; pp. 716 - 741
• Main Authors: Sajjadi, Mohaddeseh, Nasrollahzadeh, Mahmoud, Jaleh, Babak, Soufi, Ghazaleh Jamalipour, Iravani, Siavash
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 09-08-2021
• Subjects: Animals; Antineoplastic Agents - administration & dosage; cancer nanotherapy; Carbon - chemistry; carbon nanotubes; carbon quantum dots; Drug Delivery Systems; Gene Transfer Techniques; Genetic Therapy - methods; graphene; graphene oxide; graphene quantum dots; Graphite - chemistry; Humans; Molecular Targeted Therapy; nanocarriers; Nanostructures - chemistry; Nanotubes, Carbon - chemistry; Neoplasms - therapy; Quantum Dots - chemistry; Targeted drug delivery; graphene oxide; Targeted drug delivery; carbon nanotubes; graphene quantum dots; carbon quantum dots; nanocarriers; cancer nanotherapy; graphene
• ISSN: 1061-186X; 1029-2330
• DOI: 10.1080/1061186X.2021.1886301

Carbon-based nanomaterials are becoming attractive materials due to their unique structural dimensions and promising mechanical, electrical, thermal, optical and chemical characteristics. Carbon nanotubes, graphene, graphene oxide, carbon and graphene quantum dots have numerous applications in diverse areas, including biosensing, drug/gene delivery, tissue engineering, imaging, regenerative medicine, diagnosis, and cancer therapy. Cancer remains one of the major health problems all over the world, and several therapeutic approaches are focussed on designing targeted anticancer drug delivery nanosystems by applying benign and less hazardous resources with high biocompatibility, ease of functionalization, remarkable targeted therapy issues, and low adverse effects. This review highlights the recent development on these carbon based-nanomaterials in the field of targeted cancer therapy and discusses their possible and promising diagnostic and therapeutic applications for the treatment of cancers.