An efficient one-pot multicomponent synthesis of 3,4-dihydropyrimidine-2-(1H)-ones/thiones/imines via a Lewis base catalyzed Biginelli-type reaction under solvent-free conditions

An efficient one-pot multicomponent synthesis of 3,4-dihydropyrimidine-2-(1H)-ones/thiones/imines via a Lewis base catalyzed Biginelli-type reaction under solvent-free conditions

3,4-Dihydropyrimidin-2(1H)-one, 3,4-dihydropyrimidin-2(1H)-thione, and 3,4-dihydropyrimidin-2(1H)-imine derivatives were synthesized by modified Biginelli cyclocondensation reaction catalyzed by triphenylphosphine as Lewis base. The structures of the synthesized compounds have been elucidated by IR,...

Full description

Saved in:
Bibliographic Details
Published in:Arabian journal of chemistry Vol. 9; no. S1; pp. S846 - S851
Main Authors: Sheik Mansoor, S., Syed Shafi, S., Zaheer Ahmed, S.
Format: Journal Article
Language:English
Published: Elsevier B.V 01-09-2016
Elsevier
Subjects:
3,4-Dihydropyrimidine
Biginelli reaction
Cyclocondensation
Triphenylphosphine
Biginelli reaction
Cyclocondensation
3,4-Dihydropyrimidine
Triphenylphosphine
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:3,4-Dihydropyrimidin-2(1H)-one, 3,4-dihydropyrimidin-2(1H)-thione, and 3,4-dihydropyrimidin-2(1H)-imine derivatives were synthesized by modified Biginelli cyclocondensation reaction catalyzed by triphenylphosphine as Lewis base. The structures of the synthesized compounds have been elucidated by IR, 1H NMR and elemental analysis.
ISSN:1878-5352
1878-5379
DOI:10.1016/j.arabjc.2011.09.018