Progesterone side-chain degradation beside hydroxylation with Rhizopus nigricans depends on the presence of nutrients

In the absence of nutrients, Rhizopus nigricans transforms progesterone into a mixture of 11 alpha-hydroxy-4-androstene-3,17-dione and 11 alpha-hydroxy-1,4-adrostadiene-3,17-dione. The same mixture is obtained by the transformation of testosterone and its acetate.

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Bibliographic Details
Published in:	Journal of steroid biochemistry Vol. 35; no. 1; p. 155
Main Authors:	Pokorná, J, Kasal, A
Format:	Journal Article
Language:	English
Published:	England 01-01-1990
Subjects:	Androstadienes - metabolism Androstenedione - analogs & derivatives Androstenedione - metabolism Chemical Phenomena Chemistry Culture Media Hydroxylation Molecular Structure Progesterone - metabolism Rhizopus - metabolism
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Description
Summary:	In the absence of nutrients, Rhizopus nigricans transforms progesterone into a mixture of 11 alpha-hydroxy-4-androstene-3,17-dione and 11 alpha-hydroxy-1,4-adrostadiene-3,17-dione. The same mixture is obtained by the transformation of testosterone and its acetate.
ISSN:	0022-4731
DOI:	10.1016/0022-4731(90)90162-L