Influence of Depression and Anxiety on Hemodialysis Patients: The Value of Multidisciplinary Care

• Published in: International journal of environmental research and public health Vol. 18; no. 7; p. 3544
• Main Authors: Delgado-Domínguez, Carlos J, Sanz-Gómez, Sergio, López-Herradón, Ana, Díaz Espejo, Beatriz, Lamas González, Olaya, de Los Santos Roig, Macarena, Berdud Godoy, Isabel, Rincón Bello, Abraham, Ramos Sánchez, Rosa
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 29-03-2021; MDPI
• Subjects: Affective disorders; Albumin; Albumins; Anxiety; Anxiety - epidemiology; Anxiety Disorders; Body composition; Calcium; Cross-Sectional Studies; Depression - epidemiology; Hemodialysis; Humans; Male; Mental depression; Mental disorders; Mental health; Mortality; Normal distribution; Patients; Psychological factors; Quality of Life; Questionnaires; Renal Dialysis; Risk analysis; Risk factors; Sociodemographics; Variables; Germany; Spain; hemodialysis; anxiety; depression; psychological inflexibility; quality of life
• ISSN: 1660-4601; 1661-7827; 1660-4601
• DOI: 10.3390/ijerph18073544

Affective disorders promote poorer outcomes in hemodialysis patients. According to the presence or not of depression/anxiety in these patients, aims were to analyze differences in sociodemographic, clinical and/or psychological factors and to identify predictors. One hundred eighty-six hemodialysis patients were classified based on their depression/anxiety status. Basal characteristics showed differences between groups where mainly male sex (Depression: OR 0.2; Anxiety: OR 0.3) albumin (Depression: OR 0.1; Anxiety: OR 0.2) and calcium levels (Depression: OR 0.5; Anxiety: OR 0.4), impaired quality of life (Depression: OR 1.4; Anxiety: OR 1.2) and psychological inflexibility (Depression: OR 1.3; Anxiety: OR 1.2) were associated (all
< 0.01) to these mental conditions. Multivariate models showed that worse quality of life (OR 1.3;
< 0.001) predicted depression while marital status (with a partner; OR 0.3;
= 0.025) and albumin levels (OR 0.1;
= 0.027) were protective factors. Depression represented a risk factor for anxiety (OR 1.2;
= 0.001), although calcium levels (OR 0.5;
= 0.039) would protect this state. Interestingly, psychological inflexibility predicted both disorders (Depression: OR 1.2,
< 0.001 and Anxiety: OR 1.1;
= 0.002). Results highlight the relevance of well-trained multidisciplinary hemodialysis units to control the influence of these factors on the presence of depression/anxiety, and thus, their impact on the patients' outcomes.