Glycine potentiates NMDA responses in rat hippocampal CA1 neurons

When superfused onto rat hippocampal slices, glycine (0.1-0.5 mM) potentiated the depolarization induced by pressure application of NMDA in normal Krebs solution and the synaptic discharge evoked by stimulation of the Schaffer collateral-commissural inputs to the CA1 pyramidal neurons bathed in Mg2+...

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Bibliographic Details

Published in:	Neuroscience letters Vol. 100; no. 1-3; p. 237
Main Authors:	Minota, S, Miyazaki, T, Wang, M Y, Read, H L, Dun, N J
Format:	Journal Article
Language:	English
Published:	Ireland 22-05-1989
Subjects:	2-Amino-5-phosphonovalerate Action Potentials - drug effects Animals Aspartic Acid - analogs & derivatives Aspartic Acid - pharmacology Glycine - pharmacology Hippocampus - drug effects Hippocampus - physiology Humans N-Methylaspartate Rats Valine - analogs & derivatives Valine - pharmacology
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