Diagnostics for Typhoid Fever: Current Perspectives and Future Outlooks for Product Development and Access

Abstract Typhoid is an enteric disease caused by Salmonella Typhi. Like many febrile illnesses, typhoid presents with nonspecific symptoms. In routine healthcare settings in low- and middle-income countries, typhoid fever is suspected and treated empirically. Though many diagnostic tests are availab...

Full description

Saved in:

Bibliographic Details
Published in:	Open forum infectious diseases Vol. 10; no. Supplement_1; pp. S17 - S20
Main Authors:	Sapkota, Jyotshna, Roberts, Tamalee, Basnyat, Buddha, Baker, Stephen, Hampton, Lee M, Dittrich, Sabine
Format:	Journal Article
Language:	English
Published:	US Oxford University Press 02-06-2023
Subjects:	Charting the Course Supplement rapid diagnostic tests typhoid diagnostics Typhi point of care tests Salmonella Typhi
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Abstract Typhoid is an enteric disease caused by Salmonella Typhi. Like many febrile illnesses, typhoid presents with nonspecific symptoms. In routine healthcare settings in low- and middle-income countries, typhoid fever is suspected and treated empirically. Though many diagnostic tests are available for typhoid diagnosis, there are currently no diagnostic tests that meet ideal requirements for sensitivity, specificity, speed, and cost-effectiveness. With introduction of typhoid conjugate vaccine, it is essential to explore the current and future typhoid approach in the context of use case and access to ensure their utilization for disease control.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Potential conflicts of interest. All authors: No reported conflicts.
ISSN:	2328-8957 2328-8957
DOI:	10.1093/ofid/ofad120