Endogenous opiates and behavior: 2001

• Published in: Peptides Vol. 23; no. 12; pp. 2307 - 2365
• Main Authors: Bodnar, Richard J, Hadjimarkou, Maria M
• Format: Book Review Journal Article
• Language: English
• Published: United States Elsevier Inc 01-12-2002
• Subjects: Animals; Behavior - physiology; Behavior, Animal - physiology; Behavioral effects; Cardiovascular Physiological Phenomena; Drug Tolerance - physiology; Eating - physiology; Endogenous opiates; Humans; Memory - physiology; Opiate system; Opioid Peptides - physiology; Pain - drug therapy; Pain - metabolism; Receptors, Opioid - physiology; Sexual Behavior - physiology; Opiate system; CPP, conditioned place preference; GFAP, glial fibrillary acidic protein; M6G, morphine-6-glucuronide; PPEr, pre-proenkephalin; Endogenous opiates; CREB, cAMP responsive element binding protein; DLF, dorsolateral funiculus; nPgi, nucleus paragigantocellularis; VNB, ventral noradrenergic bundle; Behavioral effects; BNST, bed nucleus of the stria terminalis; Pgp, P-glycoprotein; HIV, human immunodeficiency virus; OFQ/N, orphanin FQ/nociceptin; Oprm, mu opioid receptor gene; 6-OHDA, 6-hydroxydopamine; AS ODN, antisense oligodeoxynucleotide; CPA, conditioned place aversion; D8-THC, delta-tetrahydrocannabinol; Nac, nucleus accumbens; PAG, periaqueductal gray; VTA, ventral tegmental area; VMN, ventromedial nucleus; POMC, pro-opioimelanocortin; LC, locus coeruleus; AgRP, agouti-related peptide; NCAM, neural cell adhesion molecules; MSH, melanocyte-stimulating hormones; M3G, morphine-3-glucuronide; CTA, conditioned taste aversion; NalBzOH, naloxone benzoylhydrazone; ACTH, adrenocorticotrophic hormone; 5-HTP, 5-hydroxytryptophan; NBNI, nor-binaltorphamine; THC, tetrahydrocannabinol; BFNA, beta-funaltrexamine; PTX, pertussis toxin; PKC, protein kinase C; vlPAG, ventrolateral periaqueductal gray; PVN, paraventricular nucleus; RVM, rostral ventromedial medulla; TMJ, temporomandibular joint; MAP, mitogen-activated protein; NOS, nitric oxide synthase; QTL, quantitative trait loci; NTI, naltrindole; NTS, nucleus of the solitary tract; CTX, cholera toxin; TENS, transcutaneous nerve stimulation; CGRP, calcitonin gene-related peptide
• ISSN: 0196-9781; 1873-5169
• DOI: 10.1016/S0196-9781(02)00306-6

This paper is the twenty-fourth installment of the annual review of research concerning the opiate system. It summarizes papers published during 2001 that studied the behavioral effects of the opiate peptides and antagonists. The particular topics covered this year include the molecular–biochemical effects and neurochemical localization studies of endogenous opioids and their receptors (
Section 2), and the roles of these opioid peptides and receptors in pain and analgesia (
Section 3); stress and social status (
Section 4); tolerance and dependence (
Section 5); learning and memory (
Section 6); eating and drinking (
Section 7); alcohol and drugs of abuse (
Section 8); sexual activity and hormones, pregnancy, development and endocrinology(
Section 9); mental illness and mood (
Section 10); seizures and neurologic disorders (
Section 11); electrical-related activity and neurophysiology (
Section 12); general activity and locomotion (
Section 13); gastrointestinal, renal and hepatic functions (
Section 14); cardiovascular responses (
Section 15); respiration and thermoregulation (
Section 16); and immunological responses (
Section 17).