HLA typing data on 100 type 1 (insulin-dependent) diabetic patients from central Italy show a negative association with DR5 rather than with DR2

HLA typing data on 100 type 1 (insulin-dependent) diabetic patients from central Italy show a negative association with DR5 rather than with DR2

HLA typing of 100 Type 1 diabetic patients from the Rome area confirmed the strong association with DR3 and DR4 and the prevalence of DR3/4 heterozygotes. However, DR5 rather than DR2 showed a significantly negative association.

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Bibliographic Details
Published in:Clinical immunology and immunopathology Vol. 45; no. 1; p. 143
Main Authors: Vela, M, Adorno, D, Longo, A, Papola, F, Maccarone, D, Centis, D, Raponi, M P, Candela, A, Campea, L, Orsini, M
Format: Journal Article
Language:English
Published: United States 01-10-1987
Subjects:
Adolescent
Adult
Child
Child, Preschool
Diabetes Mellitus, Type 1 - immunology
Female
HLA-D Antigens - analysis
HLA-DR Antigens - analysis
HLA-DR2 Antigen
HLA-DR3 Antigen
HLA-DR4 Antigen
HLA-DR5 Antigen
Humans
Italy
Male
Italy
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Description
Summary:HLA typing of 100 Type 1 diabetic patients from the Rome area confirmed the strong association with DR3 and DR4 and the prevalence of DR3/4 heterozygotes. However, DR5 rather than DR2 showed a significantly negative association.
ISSN:0090-1229
DOI:10.1016/0090-1229(87)90121-8