Somatostatin-14 and somatostatin-28 levels are light-driven and vary during development in the chicken retina

• Published in: Brain research. Developmental brain research Vol. 78; no. 1; p. 65
• Main Authors: Dowton, M, Boelen, M K, Morgan, I G
• Format: Journal Article
• Language: English
• Published: Netherlands 18-03-1994
• Subjects: Aging - metabolism; Animals; Chickens; Chromatography, High Pressure Liquid; Darkness; Light; Molecular Sequence Data; Retina - growth & development; Retina - metabolism; Somatostatin - immunology; Somatostatin - metabolism; Somatostatin-28
• ISSN: 0165-3806
• DOI: 10.1016/0165-3806(94)90010-8

The relative levels of somatostatin-14 and somatostatin-28 were determined during both perinatal development and variations in lighting conditions in the chicken retina. During perinatal development of the retina, somatostatin-14 predominated in recently hatched chickens, whereas somatostatin-28 predominated in the retinas of older chickens. In mature chickens, the levels of both somatostatin-14 and somatostatin-28 increased during the light and decreased during the dark. Our results suggest that these two forms of somatostatin are released proportionally and in parallel.