Cytogenetics of a cell line derived from an ovarian papillary serous cystadenocarcinoma

Cytogenetics of a cell line derived from an ovarian papillary serous cystadenocarcinoma

The cell line OAW 42 was established from the ascites of a patient with papillary serous cystadenocarcinoma of the ovary. Cytogenetic analysis at three different passages showed that the line was hypotetraploid, with no distinct mode, and was characterized by 14 stable markers, involving chromosomes...

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Bibliographic Details
Published in:Cancer genetics and cytogenetics Vol. 12; no. 4; p. 321
Main Authors: Hill, S M, Rodgers, C S, Hultén, M A, Wilson, A P
Format: Journal Article
Language:English
Published: United States 01-01-1984
Subjects:
Aneuploidy
Cell Line
Chromosome Aberrations
Chromosome Banding
Cystadenocarcinoma - genetics
Female
Humans
Karyotyping
Ovarian Neoplasms - genetics
Translocation, Genetic
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Summary:The cell line OAW 42 was established from the ascites of a patient with papillary serous cystadenocarcinoma of the ovary. Cytogenetic analysis at three different passages showed that the line was hypotetraploid, with no distinct mode, and was characterized by 14 stable markers, involving chromosomes #1, #3, #4, #5, #12, #17, #18, #20, and #21. Neither component of the translocation t(6;14)(q21;q24), previously reported to characterize ovarian papillary serous cystadenocarcinoma, was found.
ISSN:0165-4608
DOI:10.1016/0165-4608(84)90065-7