Chronic Proliferative Rhinitis associated with Salmonella enterica subspecies diarizonae serovar 61:k:1, 5, (7) in Sheep in Spain

• Published in: Journal of comparative pathology Vol. 147; no. 4; pp. 406 - 409
• Main Authors: Lacasta, D., Ferrer, L.M., Ramos, J.J., Bueso, J.P., Borobia, M., Ruiz de Arcaute, M., Figueras, L., González-Sainz, J.M., De las Heras, M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01-11-2012
• Subjects: adults; Animals; antigens; Autopsy; bacteria; Bone; Cell Proliferation; Chronic Disease; chronic rhinitis; Epithelial cells; Epithelium; flocks; histopathology; immunohistochemistry; lamina propria; Leukocytes (neutrophilic); Macrophages; Microorganisms; Mucosa; Mucus; necropsy; neutrophils; Neutrophils - pathology; Nose; Plasma cells; Polyps; Polyps - pathology; Rasa Aragonesa; Rhinitis; Rhinitis - microbiology; Rhinitis - pathology; Rhinitis - veterinary; Salmonella enterica; Salmonella enterica - isolation & purification; Salmonella Infections, Animal - microbiology; Salmonella Infections, Animal - pathology; serotypes; Sheep; sheep diseases; Sheep Diseases - microbiology; Sheep Diseases - pathology; Spain - epidemiology; Turbinates - pathology; Wheezing; zoonoses; Spain; Salmonella enterica; sheep; chronic rhinitis
• ISSN: 0021-9975; 1532-3129
• DOI: 10.1016/j.jcpa.2012.03.004

A chronic proliferative rhinitis in sheep associated with Salmonella enterica subspecies diarizonae serovar 61:k:1, 5, (7) is described. Ten adult sheep from eight traditionally managed Rasa Aragonesa flocks located in Aragon (Spain) were studied. Clinical signs began with bilateral thick mucus nasal discharge, wheezing and snoring and progressed to partial or complete obstruction of the nostrils. Necropsy examination revealed swollen ventral nasal turbinates with a roughened mucosal surface partially covered by small polyps. Histopathology revealed chronic proliferative rhinitis with a predominant population of neutrophils that infiltrated the mucosal epithelium. Plasma cells and macrophages were present in the lamina propria. Organisms expressing Salmonella antigen immunohistochemically were detected within epithelial cells. Salmonella enterica subspecies diarizonae serovar 61:k:1, 5, (7) was isolated as a sole microorganism from nasal swabs taken from five animals. The implication of finding this bacterium in various diseases in sheep and its role as a potential zoonosis are discussed.