Premarin-induced ischemic colitis

There are numerous literature reports of oral contraceptive-induced (estrogen and progesterone) ischemic bowel disease. However, Premarin-induced (equine conjugated estrogen) intestinal ischemia has rarely been reported. We describe three cases of Premarin-induced ischemic colitis. In contrast to or...

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Bibliographic Details
Published in:	Journal of clinical gastroenterology Vol. 19; no. 2; p. 108
Main Authors:	Gurbuz, A K, Gurbuz, B, Salas, L, Rosenshein, N B, Donowitz, M, Giardiello, F M
Format:	Journal Article
Language:	English
Published:	United States 01-09-1994
Subjects:	Adult Colitis, Ischemic - chemically induced Estrogens, Conjugated (USP) - adverse effects Female Humans Male Middle Aged
Online Access:	Get more information
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Summary:	There are numerous literature reports of oral contraceptive-induced (estrogen and progesterone) ischemic bowel disease. However, Premarin-induced (equine conjugated estrogen) intestinal ischemia has rarely been reported. We describe three cases of Premarin-induced ischemic colitis. In contrast to oral contraceptive-induced ischemic colitis, Premarin-induced ischemia is restricted to the colon, has not required surgical therapy, can have a chronic or chronic intermittent course, may be reversible despite continued usage of Premarin, and may present with nonspecific abdominal and colonic symptoms.
ISSN:	0192-0790
DOI:	10.1097/00004836-199409000-00006