Sleepwalking, sleep-related eating disorder and sleep-related smoking successfully treated with topiramate: a case report

• Published in: Sleep science (São Paulo, SP ) Vol. 15; no. 3; pp. 370 - 373
• Main Authors: Kazi, Sana Elham, Mohammed, Jamal Mujaddid M, Schenck, Carlos H
• Format: Journal Article
• Language: English
• Published: Brazilian Association of Sleep and Latin American Federation of Sleep 01-01-2022; Thieme Revinter Publicações Ltda
• Subjects: Case Reports; nocturnal smoking; parasomnias; sleep-related eating disorder; sleep-related smoking; somnambulism; topiramate
• ISSN: 1984-0659; 1984-0063
• DOI: 10.5935/1984-0063.20220065

We describe a 45-year-old married woman with sleepwalking, sleep-related eating disorder, and sleep-related smoking behavior, but without restless legs syndrome. The patient had a history of mild obstructive sleep apnea with an AHI of 12.6/hour with an oxygen saturation nadir of 95%, which resolved after bariatric surgery. Treatment with topiramate 100mg at bedtime controlled all three parasomnias for ten months at the latest follow-up, with relapse occurring whenever topiramate was stopped. To our knowledge, this is the first reported successful treatment of sleep-related smoking. Clinicians are encouraged to inquire about other types of parasomnias, and other sleep disorders such as narcolepsy, in patients presenting with a complaint of one parasomnia.