Locally Advanced Stage High-Grade Mucoepidermoid Carcinoma of Salivary Gland in a 9-Year-Old Girl: The Controversy of Adjuvant Therapy

Locally Advanced Stage High-Grade Mucoepidermoid Carcinoma of Salivary Gland in a 9-Year-Old Girl: The Controversy of Adjuvant Therapy

Malignant salivary gland tumors are rare in children, mostly represented by low-grade mucoepidermoid carcinomas. For these patients, long-term survival rates above 95% are reported after surgical resection. Here we report a case of a 9-year-old girl with a high grade locally advanced mucoepidermoid...

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Bibliographic Details
Published in:Rare tumors Vol. 8; no. 3; pp. 6429 - 128
Main Authors: Martínez, Olga Micol, Dorado, Elena Daghoum, García, María Dolores Amorós, Ramírez, María Isabel Oviedo, de la Fuente Muñoz, Isabel, Soler, Jose Luis Fuster
Format: Journal Article
Language:English
Published: England PAGEPress Scientific Publications, Pavia, Italy 06-10-2016
PAGEPress Publications, Pavia, Italy
SAGE Publishing
Subjects:
carcinoma
Case Report
children
High-grade
mucoepidermoyd
mucoepidermoyd
High-grade
carcinoma
children
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Summary:Malignant salivary gland tumors are rare in children, mostly represented by low-grade mucoepidermoid carcinomas. For these patients, long-term survival rates above 95% are reported after surgical resection. Here we report a case of a 9-year-old girl with a high grade locally advanced mucoepidermoid carcinoma undergoing adjuvant radiotherapy and chemotherapy after surgery. We emphasize the controversy and lack of evidence-based indication for these highly toxic adjuvant therapy modalities in children.
Bibliography:Contributions: OMM, EDD and JLFS were the principal writers of the manuscript. MDAG provided information regarding the surgical approach. MIOR provided information and images regarding pathology report. IFM provided information regarding radiation therapy. IFM and MDAG revised the manuscript.
Conflict of interest: the authors declare no potential conflict of interest.
ISSN:2036-3605
2036-3613
2036-3613
DOI:10.4081/rt.2016.6429