New onset refractory status epilepticus secondary to HIV CNS viral escape syndrome: Case report

• Published in: Seizure (London, England) Vol. 94; pp. 112 - 114
• Main Authors: Al-Chalabi, Mustafa, Amsdell, Jennifer, Iftikhar, Saffa, Hollingshead, Caitlyn, Rashid, Mehmood, Sheikh, Ajaz
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01-01-2022
• Subjects: Acute Disease; Electroencephalography - adverse effects; HIV CNS escape syndrome; HIV encephalitis; HIV Infections - complications; Humans; NORSE; Status Epilepticus - etiology; HIV CNS escape syndrome; NORSE; HIV encephalitis
• ISSN: 1059-1311; 1532-2688
• DOI: 10.1016/j.seizure.2021.11.027

•HIV CNS escape syndrome is characterized by high viral load in the CNS despite having low serum viral load.•The neurological manifestation of HIV CNS escape syndrome include acute onset of headache, tremors, cognitive impairment, focal neurologic deficit, seizures, behavioral disturbance, and dysarthria.•New onset refractory status epilepticus is a rare sequalae of HIV CNS escape syndrome.•It is critical to consider HIV CNS escape syndrome early on during the investigation of NORSE as it requires changing anti-viral treatment.