Summary of the clinical practice manual for late‐onset hypogonadism

• Published in: International journal of urology Vol. 30; no. 5; pp. 422 - 430
• Main Authors: Ide, Hisamitsu, Akehi, Yuko, Fukuhara, Shinichiro, Ohira, Shin, Ogawa, Sumito, Kataoka, Tomoya, Kumagai, Hiroshi, Kobayashi, Ko, Komiya, Akira, Shigehara, Kazuyoshi, Syuto, Takahiro, Soh, Jintetu, Tanabe, Makito, Taniguchi, Hisanori, Chiba, Koji, Matsushita, Kazuhito, Mitsui, Yozo, Yoneyama, Takahiro, Shirakawa, Tomoya, Fujii, Yasuhisa, Kumano, Hiroaki, Ueshiba, Hajime, Amano, Toshiyasu, Sasaki, Haruaki, Maeda, Seiji, Mizokami, Atsushi, Suzuki, Kazuhiro, Horie, Shigeo
• Format: Journal Article
• Language: English
• Published: Australia Wiley Subscription Services, Inc 01-05-2023
• Subjects: aging; Angina; Arteriosclerosis; Dementia disorders; erectile dysfunction; Hormone Replacement Therapy; Humans; Hypogonadism; Hypogonadism - diagnosis; Hypogonadism - drug therapy; late‐onset hypogonadism; Metabolic syndrome; Metabolic Syndrome - diagnosis; Obesity; Testosterone; Testosterone - therapeutic use; aging; testosterone; late-onset hypogonadism; erectile dysfunction
• ISSN: 0919-8172; 1442-2042
• DOI: 10.1111/iju.15160

Testosterone plays an important role in maintaining both physical and mental function. Age‐related testosterone depletion contributes to the development of angina, arteriosclerosis, obesity, metabolic syndrome, dementia, frailty, and a range of other conditions. A condition involving age‐related testosterone depletion and the associated clinical symptoms is defined as late‐onset hypogonadism (LOH). LOH is treated by testosterone replacement therapy. Indications for testosterone replacement therapy are determined by evaluating symptoms and signs.