Reperfusion ventricular fibrillation during coronary artery bypass operations and its association with postoperative enzyme release

• Published in: The Journal of thoracic and cardiovascular surgery Vol. 93; no. 2; p. 247
• Main Authors: Lockerman, Z S, Rose, D M, Cunningham, Jr, J N, Lichstein, E
• Format: Journal Article
• Language: English
• Published: United States 01-02-1987
• Subjects: Aged; Coronary Artery Bypass; Creatine Kinase - blood; Female; Humans; Intraoperative Care; Isoenzymes; Male; Middle Aged; Monitoring, Physiologic; Postoperative Period; Time Factors; Ventricular Fibrillation - enzymology; Ventricular Fibrillation - etiology
• ISSN: 0022-5223
• DOI: 10.1016/s0022-5223(19)36447-5

Elevated creatine kinase MB level is the most common marker of myocardial infarction in patients who have had a recent coronary bypass operation. This study was performed to determine whether there is any relationship between reperfusion rhythms, their treatment, and postoperative creatine kinase MB concentrations. Twenty patients were monitored during coronary bypass operations. Four patients had no reperfusion ventricular fibrillation and no elevation of creatine kinase MB postoperatively. Of the 16 remaining patients, all had ventricular fibrillation and 12 had an elevation of postoperative creatine kinase MB (p less than 0.015). There was also a 75% correlation between the time in ventricular fibrillation and postoperative creatine kinase MB level. There was no correlation between other measured parameters, such as cross-clamp time, bypass time, or the number of defibrillations. It is concluded that reperfusion ventricular fibrillation is associated with release of creatine kinase MB, and the time in ventricular fibrillation is correlated with the postoperative creatine kinase MB level.