Blue-violet light-emitting diode irradiation in combination with hemostatic gelatin sponge (Spongel) application ameliorates immediate socket bleeding in patients taking warfarin

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology Vol. 117; no. 2; pp. 170 - 177
• Main Authors: Okamoto, Toshihiro, DDS, PhD, Ishikawa, Isao, DDS, PhD, Kumasaka, Akira, DDS, Morita, Seigo, DDS, Katagiri, Sayaka, DDS, PhD, Okano, Teruo, DEng, PhD, Ando, Tomohiro, DDS, PhD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-02-2014
• Subjects: Adult; Aged; Aged, 80 and over; Dentistry; Female; Gelatin - therapeutic use; Hemostatics - therapeutic use; Humans; Male; Middle Aged; Oral Hemorrhage - etiology; Oral Hemorrhage - prevention & control; Phototherapy - methods; Postoperative Hemorrhage - etiology; Postoperative Hemorrhage - prevention & control; Surgery; Surgical Sponges; Tooth Extraction; Treatment Outcome; Warfarin - administration & dosage
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2013.09.009

Objective The control of bleeding after tooth extraction is a major concern in patients taking warfarin. Light-emitting diode (LED) irradiation with hemostatic gelatin sponge application was investigated. Study Design Patients who took warfarin and required tooth extraction were divided randomly into 3 groups. The first group was irradiated with blue-violet LED after tooth extraction. The second group was treated with a hemostatic gelatin sponge and LED irradiation. The third group was treated with only hemostatic gelatin sponges. Hemostasis was evaluated at 30 seconds after treatment. Results Less than 30% of the patients achieved hemostasis within 30 seconds in the hemostatic sponge group; approximately 50% of the patients in the simple LED irradiation group achieved hemostasis within 30 seconds; and 86.7% of the patients in the LED and hemostatic sponge combined group achieved hemostasis within 30 seconds, indicating that combined treatment with LED and hemostatic sponges provided a significantly higher hemostasis than in the hemostatic sponge group ( P < .01). Conclusions Blue-violet LED irradiation combined with hemostatic gelatin sponge treatment yielded hemostasis of the extraction socket within 30 seconds without suture in most cases.