Exercise as a therapeutic intervention in chronic kidney disease: are we nearly there yet?

• Published in: Current opinion in nephrology and hypertension Vol. 32; no. 6; pp. 502 - 508
• Main Authors: Castle, Ellen M, Billany, Roseanne E, Lightfoot, Courtney J, Annema, Coby, De Smet, Stefan, Graham-Brown, Matthew P M, Greenwood, Sharlene A
• Format: Journal Article
• Language: English
• Published: England Lippincott Williams & Wilkins 01-11-2023
• Subjects: COVID-19; DIAGNOSTICS AND TECHNIQUES: Edited by Maarten W. Taal; Exercise; Humans; Kidney; Quality of Life; Renal Insufficiency, Chronic - therapy
• ISSN: 1062-4821; 1473-6543; 1473-6543
• DOI: 10.1097/MNH.0000000000000923

The opportunity to review the more recent evidence for prescribing exercise-based physical rehabilitation for people living with chronic kidney disease (CKD) is timely. There has been a recent global focus evaluating how physical activity interventions might improve health-related quality of life and outcomes for people living with chronic health conditions in a post-COVID era. There is finally a long overdue commitment from the kidney research and clinical community to deliver pragmatic interventions to help people living with CKD to be able to live well with their condition.
This article reviews recent research, and discusses the challenges and potential solutions, for providing exercise-based therapeutic options for people living with CKD; including predialysis self-management interventions, options for both prehabilitation and posttransplant rehabilitation, pragmatic considerations for delivery of exercise therapy for people receiving haemodialysis treatment and the role of virtual kidney-specific rehabilitation.
Whilst there remains a need for further research in this area of patient care, there is now a body of evidence and kidney-specific guidelines that firmly support a rollout of pragmatic and scalable exercise-based interventions for people living with CKD. We are indeed nearly there now.