Transurethral Incisions for Bladder Neck Contracture: Comparable Results without Intralesional Injections

• Published in: Journal of clinical medicine Vol. 11; no. 15; p. 4355
• Main Authors: Nealon, Samantha W, Bhanvadia, Raj R, Badkhshan, Shervin, Sanders, Sarah C, Hudak, Steven J, Morey, Allen F
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 27-07-2022; MDPI
• Subjects: Bladder; Body mass index; Clinical medicine; Diabetes; Endoscopy; Intubation; Patients; Prostate; Radiation; Surgical outcomes; Urological surgery; United States > US; artificial urinary sphincter; transurethral incision of bladder neck contracture; balloon dilation; adjunctive intralesional injections
• ISSN: 2077-0383; 2077-0383
• DOI: 10.3390/jcm11154355

To present our 12-year experience using an endoscopic approach to manage bladder neck contracture (BNC) without adjunctive intralesional agents and compare it to published series not incorporating them, we retrospectively reviewed 123 patients treated for BNC from 2008 to 2020. All underwent 24 Fr balloon dilation followed by transurethral incision of BNC (TUIBNC) with deep incisions at 3 and 9 o'clock using a Collins knife without the use of intralesional injections. Success was defined as a patent bladder neck and 16 Fr cystoscope passage into the bladder two months later. Most with recurrent BNC underwent repeat TUIBNC. Success rates, demographics, and BNC characteristics were analyzed. The etiology of BNC in our cohort was most commonly radical prostatectomy with or without radiation (36/123, 29.3%, 40/123, 32.5%). Some had BNC treatment prior to referral (30/123, 24.4%). At 12-month follow-up, bladder neck patency was observed in 101/123 (82.1%) after one TUIBNC. An additional 15 patients (116/123, 94.3%) had success after two TUIBNCs. On univariate and multivariate analyses, ≥2 endoscopic treatments was the only factor associated with failure. TUIBNC via balloon dilation and deep bilateral incisions without the use of adjunctive intralesional injections has a high patency rate. History of two or more prior endoscopic procedures is associated with failure.