Dietary vitamin A deficiencies and stomach cancer

The hypothesis of vitamin A intake deficiencies serving as an antecedent factor in the development of stomach cancer was assessed employing a case-control design. Interviews of proxy informants for 111 cases and a pair-matched control group were conducted using a food frequency questionnaire from wh...

Full description

Saved in:

Bibliographic Details
Published in:	American journal of epidemiology Vol. 121; no. 1; p. 65
Main Authors:	Stehr, P A, Gloninger, M F, Kuller, L H, Marsh, G M, Radford, E P, Weinberg, G B
Format:	Journal Article
Language:	English
Published:	United States 01-01-1985
Subjects:	Analysis of Variance Arteriosclerosis - etiology Death Certificates Diet Epidemiologic Methods Ethnic Groups Female Humans Male Pennsylvania Sex Factors Stomach Neoplasms - epidemiology Stomach Neoplasms - etiology Vitamin A Deficiency - complications Pennsylvania
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The hypothesis of vitamin A intake deficiencies serving as an antecedent factor in the development of stomach cancer was assessed employing a case-control design. Interviews of proxy informants for 111 cases and a pair-matched control group were conducted using a food frequency questionnaire from which an averaged vitamin A intake index was calculated. Stomach cancer cases showed a significantly higher proportion with lowered total vitamin A intake levels (odds ratio = 1.71) which remained constant across sex and socioeconomic status groupings. These results demonstrated a consistency with previous related studies vis-à-vis the strength and specificity of the putative association, a moderate (but statistically nonsignificant) dose-response curve, proper temporal association, and biologic plausibility.
ISSN:	0002-9262
DOI:	10.1093/oxfordjournals.aje.a113984