The nucleotide sequence of Saccharomyces cerevisiae chromosome VII

• Published in: Nature (London) Vol. 387; no. 6632 Suppl; pp. 81 - 84
• Main Authors: Tettelin, H, Agostoni Carbone, M L, Albermann, K, Albers, M, Arroyo, J, Backes, U, Barreiros, T, Bertani, I, Bjourson, A J, Brückner, M, Bruschi, C V, Carignani, G, Castagnoli, L, Cerdan, E, Clemente, M L, Coblenz, A, Coglievina, M, Coissac, E, Defoor, E, Del Bino, S, Delius, H, Delneri, D, de Wergifosse, P, Dujon, B, Kleine, K
• Format: Journal Article Web Resource
• Language: English
• Published: England Nature Publishing Group 29-05-1997
• Subjects: Base Sequence; Chromosomes, Fungal; Deoxyribonucleic acid; DNA; DNA, Fungal; Fungal Proteins - genetics; Genes; Humans; Life sciences; Microbiologie; Microbiology; Open Reading Frames; Saccharomyces cerevisiae - genetics; Sciences du vivant; Sequence Homology, Amino Acid; Yeast
• ISSN: 0028-0836; 1476-4687; 1476-4687
• DOI: 10.1038/387s081

The complete nucleotide sequence of Saccharomyces cerevisiae chromosome VII has 572 predicted open reading frames (ORFs), of which 341 are new. No correlation was found between G+C content and gene density along the chromosome, and their variations are random. Of the ORFs, 17% show high similarity to human proteins. Almost half of the ORFs could be classified in functional categories, and there is a slight increase in the number of transcription (7.0%) and translation (5.2%) factors when compared with the complete S. cerevisiae genome. Accurate verification procedures demonstrate that there are less than two errors per 10,000 base pairs in the published sequence.