Epidemiology of Bladder Cancer

Bladder cancer incidence is higher in old men, shows geographic variation, and is mostly an environmental disease. Cigarette smoking, occupational exposures, water arsenic, Schistosoma haematobium infestation, and some medications are the best established risk factors. Low-penetrance genetic factors...

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Bibliographic Details
Published in:	Hematology/oncology clinics of North America Vol. 29; no. 2; pp. 177 - 189
Main Authors:	Malats, Núria, MD, PhD, MPH, Real, Francisco X., MD, PhD
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-04-2015
Subjects:	Animals Arsenic Bladder cancer Genetic susceptibility Hematology, Oncology and Palliative Medicine Humans Incidence Incidence and prevalence Occupational risk factors Prevalence Risk Factors Smoking Urinary Bladder Neoplasms - epidemiology Urinary Bladder Neoplasms - etiology Urothelium Arsenic Genetic susceptibility Incidence and prevalence Occupational risk factors Bladder cancer Urothelium Smoking
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Summary:	Bladder cancer incidence is higher in old men, shows geographic variation, and is mostly an environmental disease. Cigarette smoking, occupational exposures, water arsenic, Schistosoma haematobium infestation, and some medications are the best established risk factors. Low-penetrance genetic factors also contribute to its origin, some through interaction with environmental factors. Bladder cancer has high prevalence and a low mortality, being largely a chronic disease. Data on environmental and genetic factors involved in the disease outcome are inconclusive.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0889-8588 1558-1977
DOI:	10.1016/j.hoc.2014.10.001