Treatment results of patients with a squamous cell carcinoma of the buccal mucosa

• Published in: Oral oncology Vol. 42; no. 8; pp. 795 - 799
• Main Authors: Coppen, Casper, de Wilde, Peter C.M., Pop, Lucas A., van den Hoogen, Franciscus J.A., Merkx, Matthias A.W.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01-09-2006; Elsevier
• Subjects: Aged; Aged, 80 and over; Biological and medical sciences; Buccal mucosa; Carcinoma, Squamous Cell - pathology; Carcinoma, Squamous Cell - radiotherapy; Carcinoma, Squamous Cell - secondary; Carcinoma, Squamous Cell - surgery; Epidemiologic Methods; Female; Follow-up; Humans; Long-Term Care; Male; Medical sciences; Middle Aged; Mouth Mucosa; Mouth Neoplasms - pathology; Mouth Neoplasms - radiotherapy; Mouth Neoplasms - surgery; Neoplasm Recurrence, Local - therapy; Neoplasm Staging; Neoplasms, Second Primary - diagnosis; Neoplasms, Second Primary - therapy; Oral cavity; Otorhinolaryngology. Stomatology; Prognosis; Radiotherapy, Adjuvant; Squamous cell carcinoma; Treatment Outcome; Tumors; Buccal mucosa; Oral cavity; Squamous cell carcinoma; Follow-up; Human; Cancerology; Treatment; Follow up study; Stomatology; Mucosa; ENT; Malignant tumor
• ISSN: 1368-8375; 1879-0593
• DOI: 10.1016/j.oraloncology.2005.11.017

The purpose of this study was to evaluate outcome and value of follow-up of squamous cell carcinoma (SCC) of the buccal mucosa in patients treated at the Radboud University Nijmegen Medical Centre, The Netherlands. A longitudinal cohort study was performed involving 32 patients treated with curative intent (surgery on indication followed by radiotherapy) for SCC of the buccal mucosa from 1987 to 2002, with a minimum follow-up of three years. The prognosis of SCC of the buccal mucosa is comparable to other sites of the oral cavity. The success rate of therapy for a local and/or regional recurrence is very limited. Patients with a second primary tumour (SPT) can be cured if the tumour is detected in an early stage. Routine follow-up used to detect local recurrence or SPT has almost no value after five years and seems of limited value after three years.