Spontaneous Kidney Allograft Rupture

• Published in: Transplantation proceedings Vol. 37; no. 7; pp. 3079 - 3080
• Main Authors: Shahrokh, H., Rasouli, H., Zargar, M.A., Karimi, K., Zargar, K.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: New York, NY Elsevier Inc 01-09-2005; Elsevier Science
• Subjects: Biological and medical sciences; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Graft Rejection - complications; Humans; Injuries of the urinary system. Foreign bodies. Diseases due to physical agents; Kidney Transplantation - adverse effects; Medical Records; Medical sciences; Postoperative Complications - epidemiology; Retrospective Studies; Rupture, Spontaneous - epidemiology; Rupture, Spontaneous - surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tissue, organ and graft immunology; Transplantation, Homologous; Traumas. Diseases due to physical agents; Kidney disease; Medicine; Urinary system disease; Treatment; Urinary system; Surgery; Spontaneous; Graft; Kidney rupture; Transplantation; Homotransplantation
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2005.07.054

Spontaneous renal allograft rupture is one of the most dangerous complications of kidney transplantation, which can result in graft loss.
This condition needs immediate surgical intervention. Conservative management has dismal results. Its prevalence varies from 0.3% to 3%. Rupture occurs in first few weeks after transplantation. Predisposing factors for graft rupture are acute rejection, acute tubular necrosis, and renal vein thrombosis. There are growing reports about successful results of repairing these ruptured kidneys. In this study, we reviewed the medical records of 1682 patients who received kidney allografts from living donors from 1986 through 2003. There were six (0.35%) cases of renal allograft rupture. All were preceded by acute graft rejection. They were treated with antirejection medications. In first three cases, the kidney allografts were removed because the procedure of choice in this situation is graft nephrectomy; but in three next cases we repaired the ruptured grafts with good results in two of them. In conclusion, the procedure of choice for kidney allograft rupture is graft repair.