Alteration in mean platelet volume and platicrit values in patients with cancer that developed thrombosis

• Published in: Clinical and applied thrombosis/hemostasis Vol. 19; no. 3; p. 331
• Main Authors: Mutlu, Hasan, Artis, Tarik A, Erden, Abdülsamet, Akca, Zeki
• Format: Journal Article
• Language: English
• Published: United States 01-06-2013
• Subjects: Adult; Aged; Blood Platelets - pathology; Female; Humans; Male; Mean Platelet Volume; Middle Aged; Neoplasms - blood; Neoplasms - complications; Prospective Studies; Thrombosis - blood; Thrombosis - epidemiology; Thrombosis - etiology; deep venous thrombosis; thrombosis prophylaxis; thrombosis
• ISSN: 1938-2723
• DOI: 10.1177/1076029611433644

Mean platelet volume (MPV) is an indicator of thrombocyte volume and tendency to thrombosis can be mentioned in case of MPV elevation. Cancers are one of the important groups of thrombotic diseases. In the present study, MPV value was scrutinized in patients with cancer that developed thrombosis. Totally 43 patients followed in Kayseri Training and Research Hospital, in who thromboembolus has been developed, were prospectively recruited in the study. Thrombocyte, MPV, and platicrit (PCT) values were recorded at the time of cancer diagnosis and thrombosis development. Frequency analysis, crosstabs, and paired samples t test were used. Analyses showed that MPV values at the time of thrombosis development were significantly low as compared to those at the time of cancer diagnosis (P = .041). Thrombocyte count and PCT values were also low but not significant. The result of the present study is likely to show that thrombocytes have ignorable effect on thrombosis development in patients with cancer.