Fibrous dysplasia of bone : case report with autopsy study 80 years after the original clinical recognition of the bone lesions

We present a report of the histological features of the bone lesions in a case of polyostotic fibrous dysplasia studied at autopsy in a patient aged 88 years. While much of the fibrous tissue of the lesions contained the trabeculae of non-lamellar bone that are a feature of fibrous dysplasia in youn...

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Bibliographic Details
Published in:	Skeletal radiology Vol. 26; no. 3; pp. 177 - 183
Main Authors:	SISSONS, H. A, MALCOLM, A. J
Format:	Journal Article
Language:	English
Published:	Berlin Springer 01-03-1997 Springer Nature B.V
Subjects:	Aged Aged, 80 and over Biological and medical sciences Diseases of the osteoarticular system Female Fibrous Dysplasia, Polyostotic - diagnostic imaging Fibrous Dysplasia, Polyostotic - pathology Humans Malformations and congenital and or hereditary diseases involving bones. Joint deformations Medical sciences Radiography Endocrinopathy Human Case study Autopsy Pseudohypoparathyroidism Diseases of the osteoarticular system Albright disease Female Osteochondrodysplasia Elderly Genetic disease
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Summary:	We present a report of the histological features of the bone lesions in a case of polyostotic fibrous dysplasia studied at autopsy in a patient aged 88 years. While much of the fibrous tissue of the lesions contained the trabeculae of non-lamellar bone that are a feature of fibrous dysplasia in young patients, other parts of the lesions showed evidence of osteoclastic remodelling of bone trabeculae, and even of the replacement of some of these structures by mature lamellar bone.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Case Study-2 ObjectType-Feature-4 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0364-2348 1432-2161
DOI:	10.1007/s002560050216