Factors affecting the occurrence, duration of hospitalization and final outcome in canine parvovirus infection

• Published in: Research in veterinary science Vol. 89; no. 2; pp. 174 - 178
• Main Authors: Iris Kalli, S. Leontides, Leonidas, E. Mylonakis, Mathios, Adamama-Moraitou, Katerina, Rallis, Timoleon, F. Koutinas, Alexander
• Format: Journal Article
• Language: English
• Published: England Elsevier India Pvt Ltd 01-10-2010; Elsevier Limited
• Subjects: Animals; Blood; Case-Control Studies; complications; Disease; disease course; Dog; dog diseases; Dog Diseases - etiology; Dog Diseases - virology; Dogs; Enteritis - therapy; Enteritis - veterinary; Enteritis - virology; Feline panleukopenia virus; Hospitalization; Infections; Mortality; Parvoviridae Infections - therapy; Parvoviridae Infections - veterinary; Parvoviridae Infections - virology; Parvovirus; Parvovirus, Canine; Prognosis; puppies; Retrospective Studies; risk factors; systemic inflammatory response syndrome; Teaching hospitals; Treatment Outcome; Veterinary medicine; Viral diarrhea; viral diseases of animals and humans; Parvovirus; Prognosis; Viral diarrhea; Dog
• ISSN: 0034-5288; 1532-2661
• DOI: 10.1016/j.rvsc.2010.02.013

The objectives of this matched case-control study in a veterinary teaching hospital were to investigate the influence of signalment and historical data on the odds of occurrence of canine parvovirus (CPV) enteritis and the potential usefulness of the clinical signs and clinicopathologic abnormalities recorded on admission as prognostic indicators of mean duration of hospitalization (DOH) and outcome of the disease. Ninety-four puppies with natural CPV enteritis and 188 age-matched controls were studied. The odds to develop CPV enteritis were higher in purebreds compared to mixed-breed puppies. Vomiting and depression at the time of admission were associated with a prolongation of DOH by 2 and 1.75
days, respectively. The lymphopenic and hypoalbuminemic dogs were hospitalized for 1.9 and 2.5 more days, respectively, compared to those without these abnormalities. The odds of non-survival were higher in those puppies with evidence of systemic inflammatory response syndrome (SIRS) at the time of admission.