Partial trisomy 5 with a carrier parent t(5p-;9p+)

• Published in: Clinical genetics Vol. 9; no. 4; p. 437
• Main Authors: Monteleone, P, Monteleone, J, Sekhon, G, Hamilton, W, Volk, S L, Grzegocki, J, Tietjens, M
• Format: Journal Article
• Language: English
• Published: Denmark 01-04-1976
• Subjects: Adult; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 4-5; Chromosomes, Human, 6-12 and X; Female; Humans; Infant, Newborn; Male; Trisomy
• ISSN: 0009-9163
• DOI: 10.1111/j.1399-0004.1976.tb02274.x

The significance of partial trisomies of the B group is as yet unknown. An infant with multiple congenital anomalies was found to have a partial trisomy 5p+ syndrome. The father of this patient demonstrated a 5/9 translocation carrier state. A discussion of the relationship of the partial 5p+ syndrome to the Cri du chat syndrome is noted. Partial trisomy 5 would not appear, as yet, to represent a clearly definable syndrome.