Myeloma's multiple morphologies

Serum electrophoresis performed on admission as part of routine blood chemistry showed a monoclonal component (MC) in the gamma range which led to further investigation for suspected multiple myeloma. Most commonly, immunoglobulin aggregates are observed in vesicular structures derived from the dila...

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Bibliographic Details
Published in:	EJHaem Vol. 5; no. 1; pp. 260 - 261
Main Authors:	Cantoni, Silvia, Galitzia, Andrea, Mancini, Valentina, Cafro, Anna Maria, Cairoli, Roberto
Format:	Journal Article
Language:	English
Published:	United States John Wiley & Sons, Inc 01-02-2024 Wiley
Subjects:	Conflicts of interest Endoplasmic reticulum Immunoglobulins Multiple myeloma Plasma Trypanosomiasis
Online Access:	Get full text
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Summary:	Serum electrophoresis performed on admission as part of routine blood chemistry showed a monoclonal component (MC) in the gamma range which led to further investigation for suspected multiple myeloma. Most commonly, immunoglobulin aggregates are observed in vesicular structures derived from the dilated rough endoplasmic reticulum, the so-called Mott cells, named after F.W. Mott, a surgeon who described this peculiar feature in the brains of monkeys affected by trypanosomiasis [ 1]. CONFLICT OF INTEREST STATEMENT No conflicts of interest to disclose.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2688-6146 2688-6146
DOI:	10.1002/jha2.813