Chemotherapy of advanced gastric cancer with 72-hour continuous intravenous 5-fluorouracil infusion at 2-week intervals
Twenty-nine patients with advanced gastric adenocarcinoma were treated with 72-hour continuous intravenous infusion of 5-fluorouracil (30 mg/kg/24 hr) at 2-week intervals. Six patients (21%) achieved partial response and four (14%) had stabilization of their disease. The median duration of partial r...
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| Published in: | Medical and pediatric oncology Vol. 11; no. 5; p. 358 |
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| Main Authors: | , |
| Format: | Journal Article |
| Language: | English |
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United States
1983
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| Abstract | Twenty-nine patients with advanced gastric adenocarcinoma were treated with 72-hour continuous intravenous infusion of 5-fluorouracil (30 mg/kg/24 hr) at 2-week intervals. Six patients (21%) achieved partial response and four (14%) had stabilization of their disease. The median duration of partial response was 8 months, with a range of 5-19 months. The median survival time for all patients from the start of chemotherapy was 8 months. Various prognostic factors important in determining response and survival are analyzed. |
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| AbstractList | Twenty-nine patients with advanced gastric adenocarcinoma were treated with 72-hour continuous intravenous infusion of 5-fluorouracil (30 mg/kg/24 hr) at 2-week intervals. Six patients (21%) achieved partial response and four (14%) had stabilization of their disease. The median duration of partial response was 8 months, with a range of 5-19 months. The median survival time for all patients from the start of chemotherapy was 8 months. Various prognostic factors important in determining response and survival are analyzed. |
| Author | MacDonald, W C Shah, A |
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| Snippet | Twenty-nine patients with advanced gastric adenocarcinoma were treated with 72-hour continuous intravenous infusion of 5-fluorouracil (30 mg/kg/24 hr) at... |
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| SubjectTerms | Adenocarcinoma - diagnosis Adenocarcinoma - drug therapy Adenocarcinoma - mortality Adult Aged Drug Administration Schedule Female Fluorouracil - administration & dosage Humans Infusions, Parenteral Male Middle Aged Stomach Neoplasms - diagnosis Stomach Neoplasms - drug therapy Stomach Neoplasms - mortality |
| Title | Chemotherapy of advanced gastric cancer with 72-hour continuous intravenous 5-fluorouracil infusion at 2-week intervals |
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