Exploration of basil (Ocimum basilicum) essential oil profiles using E-nose and GC–MS combined with GC-O and inhalation effects on the human EEG topography and tomography (s-LORETA) and blood pressure

• Published in: Journal of functional foods Vol. 112; p. 105918
• Main Authors: Hong, Seong Jun, Kim, Da-Som, Jo, Seong Min, Yoon, Sojeong, Jeong, Hyangyeon, Yoon, Moon Yeon, Kim, Jae Kyeom, Kim, Young Jun, Shin, Eui-Cheol
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01-01-2024; Elsevier
• Subjects: Basil (Ocimum basilicum) essential oil; Blood pressure; EEG technique; Inhalation; sLORETA; EEG technique; Blood pressure; sLORETA; Basil (Ocimum basilicum) essential oil; Inhalation
• ISSN: 1756-4646; 2214-9414
• DOI: 10.1016/j.jff.2023.105918

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•Volatile compounds and odor-active compounds were detected in basil essential oil by GC–MS-O combined with electronic nose, and linalool (668.43 ± 338.82 ug/100 g) was identified as a key volatile compound.•Inhalation of basil essential oil decreased blood pressure and pulse levels of participants.•Beta waves Brodmann 38 area were activated by inhalation of basil essential oil.
This study aimed to investigate the changes in human EEG activity, Brodmann area, and blood pressure during basil essential oil inhalation. Seven odor-active compounds were detected by GC–MS combined with GC–olfactometry, and three abundant volatile compounds were detected by electronic nose. Linalool was simultaneously regarded as a major volatile compound. The systolic and diastolic blood pressures and pulse levels showed a decreasing trend during BEO inhalation. The relative beta and gamma waves in most brain regions changed during BEO inhalation. The gamma waves decreased, whereas the beta waves increased during BEO inhalation. In particular, the beta waves in the left frontal and right parietal regions and Brodmann area 38 significantly increased during inhalation using sLORETA. Accordingly, these results were highly associated with reduced stress responses by decreased gamma waves, blood pressures, and pulse levels and improved language-related functions by the increased beta wave at Brodmann area 38.