Comparison of testosterone, FSH, LH and E2 hormone levels in infertility suspected males with COVID-19 infection
Coronavirus disease 2019 (COVID-19) is an infectious disease that has many adverse impacts on many systems including reproduction. The direct effects of COVID-19 on urogenital system are still open to argue. This study aimed to compare testosterone, follicle-stimulating hormone (FSH), luteinizing ho...
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| Published in: | Medicine (Baltimore) Vol. 102; no. 43; p. e35256 |
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Lippincott Williams & Wilkins
27-10-2023
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| Abstract | Coronavirus disease 2019 (COVID-19) is an infectious disease that has many adverse impacts on many systems including reproduction. The direct effects of COVID-19 on urogenital system are still open to argue. This study aimed to compare testosterone, follicle-stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) hormone levels in COVID-19 infected male individuals with infertility suspicion.
One hundred five control (healthy) and 105 COVID-19 infected males aged between 20 to 54 years old were enrolled in the study. All patients were either diagnosed with primary or secondary infertility suspicion. The COVID-19 infection was diagnosed via reverse-transcription polymerase chain reaction test. Blood samples from patients were analyzed from the control and COVID-19 group to measure serum testosterone, FSH, LH, and E2 levels. Hormone levels were statistically compared between groups with the Independent T test.
In control and COVID-19 patients, no significance was determined for FSH and LH hormone values. Testosterone hormone were significantly decreased and E2 level was statistically increased in COVID-19 patients compared to that in the control group (P < .001).
COVID-19 is a viral disease that affects organ including gonads. COVID-19 infection decreased testosterone levels and increased E2 levels, which leading to disorders in male and female reproductivity. |
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| AbstractList | BACKGROUNDCoronavirus disease 2019 (COVID-19) is an infectious disease that has many adverse impacts on many systems including reproduction. The direct effects of COVID-19 on urogenital system are still open to argue. This study aimed to compare testosterone, follicle-stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) hormone levels in COVID-19 infected male individuals with infertility suspicion.METHODSOne hundred five control (healthy) and 105 COVID-19 infected males aged between 20 to 54 years old were enrolled in the study. All patients were either diagnosed with primary or secondary infertility suspicion. The COVID-19 infection was diagnosed via reverse-transcription polymerase chain reaction test. Blood samples from patients were analyzed from the control and COVID-19 group to measure serum testosterone, FSH, LH, and E2 levels. Hormone levels were statistically compared between groups with the Independent T test.RESULTSIn control and COVID-19 patients, no significance was determined for FSH and LH hormone values. Testosterone hormone were significantly decreased and E2 level was statistically increased in COVID-19 patients compared to that in the control group (P < .001).CONCLUSIONCOVID-19 is a viral disease that affects organ including gonads. COVID-19 infection decreased testosterone levels and increased E2 levels, which leading to disorders in male and female reproductivity. Coronavirus disease 2019 (COVID-19) is an infectious disease that has many adverse impacts on many systems including reproduction. The direct effects of COVID-19 on urogenital system are still open to argue. This study aimed to compare testosterone, follicle-stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) hormone levels in COVID-19 infected male individuals with infertility suspicion. One hundred five control (healthy) and 105 COVID-19 infected males aged between 20 to 54 years old were enrolled in the study. All patients were either diagnosed with primary or secondary infertility suspicion. The COVID-19 infection was diagnosed via reverse-transcription polymerase chain reaction test. Blood samples from patients were analyzed from the control and COVID-19 group to measure serum testosterone, FSH, LH, and E2 levels. Hormone levels were statistically compared between groups with the Independent T test. In control and COVID-19 patients, no significance was determined for FSH and LH hormone values. Testosterone hormone were significantly decreased and E2 level was statistically increased in COVID-19 patients compared to that in the control group (P < .001). COVID-19 is a viral disease that affects organ including gonads. COVID-19 infection decreased testosterone levels and increased E2 levels, which leading to disorders in male and female reproductivity. |
| Author | Afşin, Muhamet Aşir, Firat Özdemir Başaran, Süreyya Gökalp Özkorkmaz, Ebru |
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| References | Alviggi (R14-20240803) 2017; 8 Omo-Aghoja (R15-20240803) 2017; 7 Geidam (R16-20240803) 2008; 49 Sengupta (R23-20240803) 2021; 19 Adhikari (R2-20240803) 2020; 9 Xu (R4-20240803) 2021; 9 Jain (R6-20240803) 2020; 12 Anifandis (R13-20240803) 2020; 41 Haghpanah (R18-20240803) 2021; 53 Barratt (R11-20240803) 2017; 23 Uadia (R12-20240803) 2015; 4 Malki (R7-20240803) 2022; 101 Jung (R8-20240803) 2007; 39 Özdemir (R1-20240803) 2020; 1 Collins (R5-20240803) 2022; 164 Koç (R9-20240803) 2021; 105 Tsolaki (R17-20240803) 2005; 8 Ali (R21-20240803) 2022; 36 Moshrefi (R22-20240803) 2021; 38 Khalili (R10-20240803) 2020; 38 He (R3-20240803) 2021; 12 Rastrelli (R19-20240803) 2021; 9 Leanza (R20-20240803) 2022; 3 |
| References_xml | – volume: 12 start-page: e9540 year: 2020 ident: R6-20240803 article-title: Effect of COVID-19 on the organs. publication-title: Cureus contributor: fullname: Jain – volume: 23 start-page: 660 year: 2017 ident: R11-20240803 article-title: The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance-challenges and future research opportunities. publication-title: Hum Reprod Update doi: 10.1093/humupd/dmx021 contributor: fullname: Barratt – volume: 7 start-page: 73 year: 2017 ident: R15-20240803 article-title: Hormonal parameters and semen microbiological pattern of infertile males: a comparative cross-sectional study in Benin City, South South Nigeria. publication-title: J West Afr Coll Surg contributor: fullname: Omo-Aghoja – volume: 4 start-page: 45 year: 2015 ident: R12-20240803 article-title: Male infertility in Nigeria: a neglected reproductive health issue requiring attention. publication-title: J Basic Clin Reprod Sci doi: 10.4103/2278-960X.161042 contributor: fullname: Uadia – volume: 9 start-page: 88 year: 2021 ident: R19-20240803 article-title: Low testosterone levels predict clinical adverse outcomes in SARS-CoV-2 pneumonia patients. publication-title: Andrology doi: 10.1111/andr.12821 contributor: fullname: Rastrelli – volume: 38 start-page: 506 year: 2020 ident: R10-20240803 article-title: Male fertility and the COVID-19 pandemic: systematic review of the literature. publication-title: World J Mens Health doi: 10.5534/wjmh.200134 contributor: fullname: Khalili – volume: 36 start-page: e24568 year: 2022 ident: R21-20240803 article-title: The influence of SARS-CoV-2 on semen parameters of infected infertile male in comparison with those that noninfected. publication-title: J Clin Lab Anal doi: 10.1002/jcla.24568 contributor: fullname: Ali – volume: 101 start-page: e29401 year: 2022 ident: R7-20240803 article-title: COVID-19 and male infertility: an overview of the disease. publication-title: Medicine (Baltim) doi: 10.1097/MD.0000000000029401 contributor: fullname: Malki – volume: 164 start-page: 33 year: 2022 ident: R5-20240803 article-title: Impact of COVID-19 on male fertility. publication-title: Urology doi: 10.1016/j.urology.2021.12.025 contributor: fullname: Collins – volume: 38 start-page: 1691 year: 2021 ident: R22-20240803 article-title: The probable destructive mechanisms behind COVID-19 on male reproduction system and fertility. publication-title: J Assist Reprod Genet doi: 10.1007/s10815-021-02097-1 contributor: fullname: Moshrefi – volume: 1 start-page: 14 year: 2020 ident: R1-20240803 article-title: Diagnosis, treatment and prevention methods of pediatric COVID-19 infection. publication-title: J Biotechnol Strategic Health Res doi: 10.34084/bshr.711208 contributor: fullname: Özdemir – volume: 12 start-page: 677701 year: 2021 ident: R3-20240803 article-title: Effect of COVID-19 on male reproductive system - a systematic review. publication-title: Front Endocrinol (Lausanne) doi: 10.3389/fendo.2021.677701 contributor: fullname: He – volume: 49 start-page: 538 year: 2008 ident: R16-20240803 article-title: Hormonal profile of men investigated for infertility at the University of Maiduguri in northern Nigeria. publication-title: Singapore Med J contributor: fullname: Geidam – volume: 8 start-page: 117 year: 2017 ident: R14-20240803 article-title: The distribution of stroma and antral follicles differs between insulin-resistance and hyperandrogenism-related polycystic ovarian syndrome. publication-title: Front Endocrinol (Lausanne) doi: 10.3389/fendo.2017.00117 contributor: fullname: Alviggi – volume: 8 start-page: 39 year: 2005 ident: R17-20240803 article-title: Serum estradiol, progesterone, testosterone, FSH and LH levels in postmenopausal women with Alzheimer’s dementia. publication-title: Hell J Nucl Med contributor: fullname: Tsolaki – volume: 105 start-page: 743 year: 2021 ident: R9-20240803 article-title: Does COVID-19 worsen the semen parameters? Early results of a tertiary healthcare center. publication-title: Urol Int doi: 10.1159/000517276 contributor: fullname: Koç – volume: 53 start-page: e13883 year: 2021 ident: R18-20240803 article-title: Potential mechanisms of SARS-CoV-2 action on male gonadal function and fertility: current status and future prospects. publication-title: Andrologia doi: 10.1111/and.13883 contributor: fullname: Haghpanah – volume: 3 start-page: 552 year: 2022 ident: R20-20240803 article-title: The possible role of SARS-CoV-2 in male fertility: a narrative review. publication-title: Endocrines doi: 10.3390/endocrines3030046 contributor: fullname: Leanza – volume: 9 start-page: 29 year: 2020 ident: R2-20240803 article-title: Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review. publication-title: Infect Dis Poverty doi: 10.1186/s40249-020-00646-x contributor: fullname: Adhikari – volume: 9 start-page: 107 year: 2021 ident: R4-20240803 article-title: Effects of SARS-CoV-2 infection on male sex-related hormones in recovering patients. publication-title: Andrology doi: 10.1111/andr.12942 contributor: fullname: Xu – volume: 39 start-page: 203 year: 2007 ident: R8-20240803 article-title: Influence of genital heat stress on semen quality in humans. publication-title: Andrologia doi: 10.1111/j.1439-0272.2007.00794.x contributor: fullname: Jung – volume: 41 start-page: 157 year: 2020 ident: R13-20240803 article-title: COVID-19 and fertility: a virtual reality. publication-title: Reprod Biomed Online doi: 10.1016/j.rbmo.2020.05.001 contributor: fullname: Anifandis – volume: 19 start-page: 423 year: 2021 ident: R23-20240803 article-title: The impact of COVID-19 on the male reproductive tract and fertility: a systematic review. publication-title: Arab J Urol doi: 10.1080/2090598X.2021.1955554 contributor: fullname: Sengupta |
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| SubjectTerms | Adult Clinical Trial/Experimental Study COVID-19 Estradiol Female Follicle Stimulating Hormone Humans Infertility, Male Luteinizing Hormone Male Middle Aged Testosterone Young Adult |
| Title | Comparison of testosterone, FSH, LH and E2 hormone levels in infertility suspected males with COVID-19 infection |
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