Host Materials Transformable in Tumor Microenvironment for Homing Theranostics

Host Materials Transformable in Tumor Microenvironment for Homing Theranostics

A pathology‐adaptive nanosystem, in which nest‐like hosts are built based on nanofibers that are transformed from i.v. injected nanoparticles under the acidic tumor microenvironment. The solid tumor is artificially modified by nest‐like hosts readily and firmly, resulting in highly efficient accumul...

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Bibliographic Details
Published in:Advanced materials (Weinheim) Vol. 29; no. 15; pp. np - n/a
Main Authors: Yang, Pei‐Pei, Luo, Qiang, Qi, Guo‐Bin, Gao, Yu‐Juan, Li, Bing‐Nan, Zhang, Jing‐Ping, Wang, Lei, Wang, Hao
Format: Journal Article
Language:English
Published: Germany Wiley Subscription Services, Inc 01-04-2017
Subjects:
cancer
Construction
Homing
Humans
Materials science
morphology
Nanofibers
Nanoparticles
Nanostructure
Neoplasms
peptides
self‐assembly
Stabilization
Strategy
Theranostic Nanomedicine
theranostics
Tumor Microenvironment
Tumors
self-assembly
peptides
theranostics
cancer
morphology
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Summary:A pathology‐adaptive nanosystem, in which nest‐like hosts are built based on nanofibers that are transformed from i.v. injected nanoparticles under the acidic tumor microenvironment. The solid tumor is artificially modified by nest‐like hosts readily and firmly, resulting in highly efficient accumulation and stabilization of guest theranostics. This strategy shows great potential for the theranostics delivery to tumors.
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ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201605869