Analysis on the serum levels of the biomarker CTX-II in professional indoor soccer players over the course of one season

The aim of this study was to analyze the blood serum levels of CTX-II in professional indoor soccer players, at three different times during one season: at the start of the pre-season, four months later (a time that marks the middle of the season) and at the end of the season. Fourteen male soccer p...

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Published in:Revista brasileira de ortopedia Vol. 50; no. 3; pp. 331 - 335
Main Authors: Severino, Rodrigo Miziara, Jorge, Pedro Baches, Martinelli, Mauro Olivo, de Lima, Marcos Vaz, Severino, Nilson Roberto, Duarte Junior, Aires
Format: Journal Article
Language:English
Published: Brazil Elsevier Editora Ltda 01-05-2015
Elsevier
Sociedade Brasileira de Ortopedia e Traumatologia
Thieme Revinter Publicações Ltda
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Summary:The aim of this study was to analyze the blood serum levels of CTX-II in professional indoor soccer players, at three different times during one season: at the start of the pre-season, four months later (a time that marks the middle of the season) and at the end of the season. Fourteen male soccer players of mean age 19 years were included. Blood samples of 3mL were collected from each individual. The samples were analyzed by means of Elisa tests. There was a significant increase in the serum level of CTX-II in the indoor soccer players, from the beginning to the end of the season (p<0.01). These data suggest that joint degradation had occurred in these soccer players, by the end of this period. It is evident that further studies are needed, with methodological rigor, so as to make an effective contribution toward precise elucidation of the etiology of this osteoarthritis and its relationship with the biomarkers, as a tool for early diagnosis. Analisar os níveis séricos sanguíneos de CTX-II em atletas profissionais de futebol de salão, em três momentos distintos durante uma temporada: no início da pré-temporada, quatro meses após (período que marca o meio da temporada) e no fim da temporada. Foram incluídos 14 atletas do gênero masculino e média de idade de 19 anos. Foram coletados 3mL de sangue de cada indivíduo. As amostras foram analisadas pelo teste do tipo Elisa. Houve aumento significativo dos níveis séricos de CTX-II nos atletas de futebol de salão, comparando-se o início e o fim de uma temporada (p<0.01). Esses dados sugerem a ocorrência de degradação articular nos atletas, ao término desse período. Fica evidente a necessidade de futuros estudos, com rigor metodológico, que possam contribuir efetivamente para a elucidação precisa da etiologia da OA e sua relação com os biomarcadores como instrumento de diagnóstico precoce.
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ISSN:2255-4971
1982-4378
2255-4971
DOI:10.1016/j.rboe.2015.04.001