Evaluation of antimicrobial susceptibilities of non-tuberculous mycobacteria against linezolid and tigecycline

Mycobacterial susceptibility testing is important for the management of nontuberculous mycobacteria (NTM) infections. The aim of the study is to determine the susceptibilities of tigecycline (TGC) and linezolid (LZD) against NTM. The study was carried out using stocks of NTM strains in the tuberculo...

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Bibliographic Details
Published in:	Indian journal of medical microbiology Vol. 40; no. 3; pp. 446 - 448
Main Authors:	Senol, Gunes, Bicmen, Can, Gunduz, Ayriz, Dereli, Sevket, Erbaycu, Ahmet
Format:	Journal Article
Language:	English
Published:	Elsevier B.V 01-07-2022
Subjects:	Antimycobacterial resistance Linezolid Non-tuberculous mycobacteria Tigecycline Linezolid Non-tuberculous mycobacteria Tigecycline Antimycobacterial resistance
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Summary:	Mycobacterial susceptibility testing is important for the management of nontuberculous mycobacteria (NTM) infections. The aim of the study is to determine the susceptibilities of tigecycline (TGC) and linezolid (LZD) against NTM. The study was carried out using stocks of NTM strains in the tuberculosis department of the microbiology laboratory. It was designed a retrospective study. LZD and TGC sensitivities of study isolates were analyzed by microdilution. Forty NTM isolates have been studied. LZD and TGC sensitivities varied according to the NTM type. It is concluded that each isolate should be individually evaluated due to variable susceptibilities to LZD and TGC.
ISSN:	0255-0857
DOI:	10.1016/j.ijmmb.2022.03.012