Histological findings of bone marrow edema pattern on MRI in osteonecrosis of the femoral head

• Published in: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association Vol. 5; no. 5; p. 520
• Main Authors: Kubo, T, Yamamoto, T, Inoue, S, Horii, M, Ueshima, K, Iwamoto, Y, Hirasawa, Y
• Format: Journal Article
• Language: English
• Published: Japan 01-09-2000
• Subjects: Adult; Bone Marrow - pathology; Edema - pathology; Female; Femur Head - pathology; Humans; Magnetic Resonance Imaging; Osteonecrosis - pathology
• ISSN: 0949-2658
• DOI: 10.1007/s007760070033

Sequential magnetic resonance imaging (MRI) was performed on a 38-year-old woman with systemic lupus erythematosus who had received corticosteroid and had developed non-traumatic osteonecrosis of the femoral head. The initial MR finding was a band lesion on the T1-weighted image, which had been present before the onset of symptoms. At the onset of symptoms, a diffuse bone marrow edema pattern, with a low signal intensity on T1 and high signal intensity on T2-weighted images, was noted around the band lesion, extending to the femoral neck. Histopathologically, this region was found to consist of serous exudate, focal interstitial hemorrhage, and mild fibrosis, without any evidence of extension of osteonecrosis. It should be noted that extension of a low signal intensity area on MRI after the onset of hip pain may not be the result of the extension of osteonecrosis, but may represent concomitant edema due to collapse.